Apexification & apexogenesis. refers to a vital pulp therapy procedure performed to encourage physiological development and formation of the root end . This article will describe requirements for case selection and review the procedures for apexogenesis and apexification in immature permanent teeth. Dent Clin North Am. Oct;28(4) Apexogenesis versus apexification. Webber RT. PMID: ; [Indexed for MEDLINE]. MeSH terms. Adolescent.

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Nonclinical and clinical data will be presented to support the recommendations, and outcomes will be presented from clinical studies. If the exposure was carious, or the traumatic exposure crown fracture, exposed pulp is longer than 24 hours, then the coronal pulpal tissues are too inflammed to survive a simple capping procedure. The MTA is sealed with a leak-proof restoration glass ionomer, for example and the patient is recalled at appropriate intervals to re-evaluate healing and continued root development.

In this case, the unhealthy pulp is removed. Drexel Hill, PA In turn, the walls of the root canal will thicken, and the tooth will become stronger.

Treatment options: apexogenesis and apexification.

The patient is recalled periodically to monitor the progress of the root-end closure, and decide whether other measures root-end surgery may be required. If the exposure is non-carious mechanical and root development is incomplete, then a true pulp capping can be attempted.


This article will describe requirements for case selection spexification review the procedures for apexogenesis and apexification in immature permanent teeth. In the absence of a vital pulp, dentin deposition is arrested.

The more mature the root becomes, the better the chance for the survival of the tooth.

If the tissues are bleeding too profusely, the MTA will be washed away; this would be an indication that the tissues remaining are still too inflammed to apexificagion. The pulp provides a matrix for binding of its cells and provides support allowing communication between the cells.

Apexogenesis This procedure encourages the root to continue development as the pulp is healed. A small preparation is made into the dentin overlying apexificcation exposure site, using a sterile diamond round bur less potential to tear the pulpal tissue vs.

Apexogenesis versus apexification.

This procedure encourages the root to continue development as the pulp is healed. The coronal portion of the canal space is then acid-etched, and a bonded composite or galss ionomer is condensed into the canal to re-enforce the root and provide more sturctural integrity.


If the pulp heals, no additional treatment will be necessary. Published by Elsevier Inc. Maintenance of pulp vitality will allow continued root development along the entire root length. When an immature tooth is affected by caries or trauma, the pulp requires proper management according apexificafion the degree of inflammation and its vitality.

This point is a judgement call, and clinical experience will dictate when enough tissue has been removed.

Apexogenesis / Apexification

If the pulp is irreversibly inflamed or necrotic, root-end closure procedures are required when the apex has not fully formed. The dental pulp is an ectomesenchymally derived connective tissue with certain unique properties such as being encased in hard tissues, which limits its collateral circulation.

In addition to immune cells, the apexificaation pulp contains odontoblasts, which are specialized cells capable of producing dentin.