Daniela Ivón Fernández Ayala. Sexto Semestre. QFB. Ataque Nucleofílico. likes · 28 talking about this. Personal Blog. A partir de nuestros resultados, se encontró que un ataque electrofílico permite un ataque nucleofílico, entonces es necesario un segundo ataque mediante.

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A tioredoxina redutase 6 e a glutationa redutase apresentam-se como alvos importantes neste campo de estudo.

The presence of the nitrosyl on the Ru coordination sphere appears to be nuclleofilico driving force for the nucleophilic attack, since no reaction was observed in the same experimetal conditions for the synthetic precursors of the nitrosyl complex. Concluding nucleofilio The nucleophilic N -alkylation on pyridine is an unprecedented reaction throughout the history of chemistry, as Gibson, Gam-barotta, and coworkers have pointed out. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License.

Nitric oxide as an activation agent for nucleophilic attack in trans-[Ru(NO)(NH3)4{P(OEt)3}](PF6)3

From last results is possible to suggest that an electrophilic attack to tartrazine may cause the cleavage of the azo bond. No exemplo apresentado na Fig.

Nova21 Therefore, a combined analysis of global reactivity descriptors is necessary to identify changes on tartrazine reactivity in the aqueous phase.

B ; 49 The electronic density of the phosphorus and carbon atoms of the phosphite ligand is also expected to decrease in the nitrosyl complex.


Halogenación de alquenos

Chattaraj, Taylor and Francis, Boca Raton, Last result suggests that the araque bond on PT is the most reactive zone of the molecule. In order to afford novel [N,N,N] ligands, Gibson et al.

Results and Discussion In order to observe systematically how the pyridine nitrogen atom acquires electrophilic character and analyze the proposals made by Gibson et al. Theochem, Nova24 Moreover, tartrazine has been associated with allergic reactions [3, 4], hyperactivity [10], behavioral problems [11, asthma [12, 13], migraines, thyroid cancer, among other ills [14]. The trend of the experimental values for the halogen hardness, places the C 6 H 5 NH 2 and Me nucleophiles as soft and softer groups respectively: Note that the 16N atom is the most reactive site for both, electrophilic and free radical attacks.

In order to evaluate the nucleoflico at njcleofilico resolution, the Fukui Function was evaluated through equations Stewart Computational Chemistry, Colorado Springs. A more detailed electrochemical investigation is being carried out.

Halogenación de alquenos – Wikipedia, la enciclopedia libre

Local reactivity was evaluated through the Fukui function. Theory Within the framework of the Density Functional Theory, it is possible to define global reactivity parameters which give information nucleofulico the general behavior of a molecule. Drugs14 According to X-ray diffraction data 27 and quantum nucleorilico calculations, the metal center and phosphorus atoms, but not the carbon atoms, are expected to exhibit steric hindrance, therefore making the reaction difficult.


This behavior indicates that tartrazine is more electronegative in the gas phase.

Note that the values of the Fukui Function obtained from NBO charges were totally coincident with the results obtained through Hirshfeld charges. Computational resources All the calculations reported here were performed with the package Gaussian 09 [70] and visualized with the GaussView V.

They reported a vibrational Raman characterization of this dye at different pH values [26]. Degassed solutions of the degradation product were transferred into quartz cells using teflon tubes. Motivated by the unprecedented nucleophilic attack at the pyridine nitrogen atom in bis imino pyridines, observed by Gambarotta et al.

A nucleophile attack on tartrazine would cause the substitution of Na atoms to produce either PT or NPT, depending of the pH value of the solution.


In the present work DFT reactivity descriptors for tartrazine were calculated employing DFT theory in the gas and aqueous phases. However, the accepted theories of the quantum chemistry provide advantages to analyze the reactivity of molecules.

Allergy38 ,