This article reviews potential anti-dengue activities from plants distributed . In the Philippines, Euphorbia hirta, known locally as “tawa–tawa”. Management of thrombocytopenia and flu-like symptoms in dengue patients with herbal water of Euphorbia hirta. Mir M, Khurshid R, Aftab R. BACKGROUND. PDF | Euphorbia hirta commonly known as Tawa-Tawa is a plant used in folklore medicine in the Philippines for the treatment of dengue.

Author: Najinn Mezisida
Country: Mauritius
Language: English (Spanish)
Genre: Business
Published (Last): 25 November 2006
Pages: 54
PDF File Size: 11.44 Mb
ePub File Size: 1.54 Mb
ISBN: 927-6-25252-931-7
Downloads: 82808
Price: Free* [*Free Regsitration Required]
Uploader: Akir

Asian Pac J Trop Biomed.

Hence, this study indicates that the E. Current prevention of dengue by potential dengue vaccine and vector control is highly cost effective [ 2245 ].

Potential anti-dengue medicinal plants: a review

The methanolic extract of M. The Philippine archipelago, consisting of about islands, is a center of endemicity and biodiversity where a large number of endemic plants have been reported to exhibit medicinal properties. Mimosa scabrella Mimosa scabrella belongs to family Fabaceae.

Table of Contents Alerts. Biological characteristics of dengue virus and potential targets for drug design. Flagellaria indica belongs to family Flagellariaceae.

About dosage preparations were administered internally by mouth while the rest were applied topically to affected areas. Traditional medicinal plants have been reported to have antiviral activity [ 495152 ] and some have been used to treat viral infections in animals and humans. Management involves supportive care. Each use reports maybe a specific disease state or a symptom. One additional article was identified by manually searching the reference lists and forward citations of included papers.

Table 6 Dosage preparation of Euphorbia hirta compounded according to plant part. An MTT assay was carried out to determine the cytotoxicity of A.


It is found throughout China and Southeast Asia. Therefore, if vaccine were produced for only one or two serotypes, the other serotypes would increase the risk of more serious illness [ 47 ]. The average monthly temperature is Balungao, 4 respondents cited the same plant for use in 7 symptoms of dengue in addition to 10 other symptoms.

Cost and disease burden of dengue in Cambodia. Methyl-hildgardtol A isolated from T. All the papers obtained from searching the databases with above search criteria were pooled together and duplicates were removed.

Journal of Tropical Medicine

To receive news and publication updates for Journal of Tropical Medicine, enter your email address in the box below. Previous study has shown that an aqueous extract of long pepper, P.

As a consequence, the search for new anti-dengue agents from medicinal plants has assumed more urgency than in the past. The number of cases rose in following decade of — with 26, cases; however, the fatality rate was down to 0.

However, a carboxy-reduced fucoidan in which glucuronic acid was converted to glucose attenuated the inhibitory activity on DENV2 infection. Cryptonemia crenulata Cryptonemia crenulata belongs to family Halymeniaceae. Cladogynos orientalis belongs to family Euphorbiaceae. The first dengue vaccine, Eeuphorbia, has been licensed in for clinical practice [ 10 ].

Int J Pharm Frontier Res. Natural products as sources of new drugs euphorbla the period — Development of a vaccine for dengue is difficult since there are four closely related, but antigenically distinct, serotypes of the virus that can cause disease [ 646 ]. There are currently no specific treatments for dengue fever [ 22 ]. View at Google Scholar M. Euphorbia hirta is another plant used in folk medicine to cure dengue fever by people in rural areas of the Philippines [ 7 ].


Potential Use of Euphorbia hirta for Dengue: A Systematic Review of Scientific Evidence

According to the present survey, it is reiterated that denyue E. Coumarin extract of A. The contour lines of the January and July isotherms indicate the potential geographical limits of the northern and southern hemispheres for year-round survival of Aedes aegyptithe principal mosquito vector of dengue viruses.

The secondary metabolites of medicinal plants comprise a variety of compounds with a wide range of biological activities [ 68 ].

Potential anti-dengue medicinal plants: a review

Herbarium specimens and photographs of the plants in their vengue habitats were submitted to the Philippine National Herbarium for authentication. Decoctions of leaves and bark are popularly administrated for dengue [ 19 ]. Boesenbergia rotunda Boesenbergia rotunda belongs to family Zingiberaceae. This review has covered only 31 potential plants that could be used in the treatment of dengue and about ten isolated active phytochemicals.

Vengue Med Chem Lett. The ethnobotanical survey conducted in Pangasinan where dengue continues to be prevalent revealed most people, especially women, used this preparation as a supportive therapy for dengue [ 19 ]. Further, the effect of E. Ragunathan M, Solomon M.

Further research is needed to determine how to target the most appropriate stages to prevent the spread of virus infection. Platelet-increasing effects of Euphorbia hirta Linn.